Synthesis of New DPP-4 Inhibitors Based on a Novel Tricyclic Scaffold.
نویسندگان
چکیده
A novel molecular scaffold has been synthesized, and its synthesis and incorporation into new analogues of biologically active molecules will be discussed. A comparison of the inhibitory activity of these compounds to the known type-2 diabetes compound (sitagliptin) against dipeptidyl peptidase-4 (DPP-4) will be shown.
منابع مشابه
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ورودعنوان ژورنال:
- ACS medicinal chemistry letters
دوره 6 3 شماره
صفحات -
تاریخ انتشار 2015